Farmacoepidemiologia
TERAPIE FARMACOLOGICHE PER ASMA E BPCO IN ITALIA: FARMACOUTILIZZAZIONE E STIMA DELLE NECESSITÀ TERAPEUTICHE APPROPRIATE

saluterespiro.jpgdi Renato Testi*, Paolo Rizzini*, Cristina Bosetti^°, Carlo La Vecchia^, Germano Bettoncelli°, Roberto W. Dal Negro**

* Centro studi Fondazione Smith Kline;
^ Istituto di Ricerche Farmacologiche Mario Negri;
^° Istituto di Biometria e Statistica Medica, Università degli Studi di Milano;
° Società Italiana di Medicina Generale;
** Divisione di Pneumologia ASL22 Reg. Veneto, Ospedale Orlandi, Bussolengo,Verona. 

 

Introduzione

Il piano sanitario nazionale 2006-2008 indica le malattie respiratorie fra le grandi patologie per le quali è necessario un intervento urgente. Le malattie respiratorie costituiscono la terza causa di morte e di queste la la BroncoPneumopatia Cronica Ostruttiva (bpco) è responsabile di circa il 50% dei decessi ed il sesso più colpito è quello maschile. All’interno del piano la bpco è considerata malattia ad elevata priorità d’intervento, per la quale esistono prospettive di prevenzione e trattamento significative.

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COST-EFFECTIVENESS AND HEALTHCARE BUDGET IMPACT IN ITALY OF INHALED CORTICOSTEROIDS AND BROCHODILATORS FOR SEVERE AND VERY SEVERE COPD PATIENTS

polmoni.jpgRoberto Dal Negro1, M Eandi2, L Pradelli3, S Iannazzo3

1Lung Dept., Orlandi General Hospital, Bussolengo, Verona, Italy; 2Clinical Pharmacology, University of Torino, Italy; 3Advanced Research, Torino, Italy


Abstract:
Current practice guidelines for the treatment of COPD recommend the use of combined inhaled corticosteroids and long-acting bronchodilators in severe and very severe patients (GOLD stages III and IV). The aim of this study was to evaluate, through a simulation model, the economic consequences of this recommendation in Italy. We developed a cost-effectiveness analysis (CEA) on five alternative therapeutic strategies (salmeterol/fluticasone, SF; formoterol/budesonide, FB; salmeterol alone, S; fluticasone alone, F; control, C).

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RATES OF ASTHMA ATTACKS IN PATIENTS WITH PREVIOUSLY INADEQUATELY CONTROLLED MILD ASTHMA TREATED IN CLINICAL PRACTICE WITH COMBINATION DRUG THERAPY: AN EXPLORATORY POST-HOC ANALYSIS

 

bmc-pulmonary-medicine-b.jpg
Robert W Dal Negro (1), Luis Borderias (2), Qiaoyi Zhang (3), Tao Fan (*3), Vasilisa Sazonov (3), Magda Guilera (4) and Stephanie D Taylor (3)



Address: (1) Bussolengo Gen. Hospital, Verona, Italy, (2) San Jorge Hospital, Huesca, Spain, (3) Merck & Co, Inc., Whitehouse Station, NJ, USA and (4) HOREurope, Barcelona, Spain


Abstract

Background: Differences could exist in the likelihood of asthma attacks in patients treated with inhaled corticosteroid (ICS), long-acting beta-agonist (LABA), and montelukast (MON) (ICS/LABA/ MON) and patients treated with an inhaled corticosteroid (ICS) and montelukast (MON) (ICS/MON).

Allegati:
Scarica questo file (BMC_Pulmonary_Medicine.pdf)Scarica l'articolo originale195 Kb0 Downloads
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CULTURAL AND LINGUISTIC TESTING OF THE HANDLING QUESTIONNAIRE: A SPECIFIC INSTRUMENT FOR ASSESSING THE PATIENT’S ACCEPTABILITY OF DRY POWDER INHALERS.

copertinamonaldi.jpg* Roberto Walter Dal Negro
** Massimo Guerriero

* Head of Lung Dept., Orlandi Hospital, Bussolengo, Verona.
** E.S.I. Department, Statistics Section, University of Verona, Via Dell’Artigliere, 19 – 37129 Verona.

  

Summary

The testing and checking phases of a questionnaire are shortly described in the present paper, being  the identification of errors due to incorrect formulation of questions  the  main issues. The theoretical methods for “testing” a questionnaire has been examined in the first section, while the testing process for a specific questionnaire for assessing the patient’s acceptability of a dry powder device (the Handling Questionnaire) has been described in the second section, together with the grading of improvement achieved. 

Allegati:
Scarica questo file (pne69-4_04dalnegro_tech_rep.pdf)Scarica l'articolo originale80 Kb0 Downloads
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ASMA BRONCHIALE E PUBLIC AWARENESS IN ITALIA: RISULTATI DELL’INDAGINE CHAOS (CHRONIC AIRWAY OBSTRUCTION SURVEY)

farmacopercorsi.jpgS. Uleri, R. W. Dal Negro

(1)Medical Advisor, Area Ricerche, Maya Idee Srl
(2)Direttore Divisione di Pneumologia, Ospedale Orlandi - Bussolengo (VR)


ABSTRACT

Despite last years advances in asthma knowledge and treatment, its management and control remains a critical issue. Many surveys on general practitioners (GPs) and patients were conducted but no data, in Italy, are collected about the public awareness.

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EFFETTI DELLA OSSIGENOTERAPIA A LUNGO TERMINE (OTLT) SULLA MORTALITÀ DI SOGGETTI CON IRC

Paola Turco, MD, PhD

 

Nei pazienti affetti da malattie polmonari in stadio avanzato, gli effetti benefici dell’ossigenoterapia in corso di ipossiemia persistente rappresentano un dato consolidato fin dai tempi dell’introduzione dell’ossigeno come agente terapeutico. 

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